BRD-K86727142_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K86727142_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BHLHE41 basic helix-loop-helix family, member e41
CAPG capping protein (actin filament), gelsolin-like
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDIT4 DNA-damage-inducible transcript 4
FHL2 four and a half LIM domains 2
FXYD3 FXYD domain containing ion transport regulator 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA3 GATA binding protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KRT7 keratin 7, type II
MLPH melanophilin
MMP7 matrix metallopeptidase 7
NELL2 NEL-like 2 (chicken)
PLA2G16 phospholipase A2, group XVI
PPAP2C phosphatidic acid phosphatase type 2C
SCGB2A2 secretoglobin, family 2A, member 2
TFF1 trefoil factor 1
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AQP3 aquaporin 3 (Gill blood group)
ASTN2 astrotactin 2
GPNMB glycoprotein (transmembrane) nmb
HSPA1A heat shock 70kDa protein 1A
LAMP3 lysosomal-associated membrane protein 3
NES nestin
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
SEPP1 selenoprotein P, plasma, 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPARCL1 SPARC-like 1 (hevin)
TPSAB1 tryptase alpha/beta 1
TUBB2A tubulin, beta 2A class IIa
VWF von Willebrand factor