BRD-K86472598_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K86472598_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANGPT1 angiopoietin 1
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C1QB complement component 1, q subcomponent, B chain
CAPN2 calpain 2, (m/II) large subunit
CD163 CD163 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CTSL cathepsin L
CYB5R1 cytochrome b5 reductase 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT4 DNA-damage-inducible transcript 4
DST dystonin
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX3 glutathione peroxidase 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IFRD1 interferon-related developmental regulator 1
JAG1 jagged 1
KLHL21 kelch-like family member 21
KRT7 keratin 7, type II
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LGALS8 lectin, galactoside-binding, soluble, 8
LYPD3 LY6/PLAUR domain containing 3
MCOLN1 mucolipin 1
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NQO2 NAD(P)H dehydrogenase, quinone 2
PLIN2 perilipin 2
RGCC regulator of cell cycle
S100P S100 calcium binding protein P
SCPEP1 serine carboxypeptidase 1
SERTAD2 SERTA domain containing 2
SIK1 salt-inducible kinase 1
SMAD3 SMAD family member 3
SQSTM1 sequestosome 1
TACC2 transforming, acidic coiled-coil containing protein 2
TCTA T-cell leukemia translocation altered
TUFT1 tuftelin 1
TXNRD1 thioredoxin reductase 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIPI1 WD repeat domain, phosphoinositide interacting 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ARMT1 acidic residue methyltransferase 1
AUTS2 autism susceptibility candidate 2
BCHE butyrylcholinesterase
BEX1 brain expressed, X-linked 1
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CD81 CD81 molecule
CDK1 cyclin-dependent kinase 1
CTSH cathepsin H
DCK deoxycytidine kinase
DPYSL2 dihydropyrimidinase-like 2
DUT deoxyuridine triphosphatase
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FOLR1 folate receptor 1 (adult)
GPER1 G protein-coupled estrogen receptor 1
HADH hydroxyacyl-CoA dehydrogenase
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LIG1 ligase I, DNA, ATP-dependent
MUC1 mucin 1, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
NPY neuropeptide Y
NSG1 neuron specific gene family member 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX3 pre-B-cell leukemia homeobox 3
PCDH9 protocadherin 9
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PTGIS prostaglandin I2 (prostacyclin) synthase
PXMP2 peroxisomal membrane protein 2, 22kDa
RBM3 RNA binding motif (RNP1, RRM) protein 3
SFRP1 secreted frizzled-related protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPINK1 serine peptidase inhibitor, Kazal type 1
STMN1 stathmin 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFF3 trefoil factor 3 (intestinal)
TMEM14A transmembrane protein 14A
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN4 tetraspanin 4
TUBB tubulin, beta class I
TYMS thymidylate synthetase
VCAN versican