BRD-K86472598_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

119 genes differentially expressed following the BRD-K86472598_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD10 ankyrin repeat domain 10
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ATF3 activating transcription factor 3
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BMP7 bone morphogenetic protein 7
CD163 CD163 molecule
CD58 CD58 molecule
CLU clusterin
CRYAB crystallin, alpha B
CXCL5 chemokine (C-X-C motif) ligand 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
FKBP14 FK506 binding protein 14, 22 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
GAP43 growth associated protein 43
GLA galactosidase, alpha
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGHM immunoglobulin heavy constant mu
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
LYPD1 LY6/PLAUR domain containing 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PNP purine nucleoside phosphorylase
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
RAE1 ribonucleic acid export 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RGS2 regulator of G-protein signaling 2
RPS11 ribosomal protein S11
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SQSTM1 sequestosome 1
SRPX sushi-repeat containing protein, X-linked
SSX1 synovial sarcoma, X breakpoint 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TWIST1 twist family bHLH transcription factor 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
AQP1 aquaporin 1 (Colton blood group)
C1ORF106 chromosome 1 open reading frame 106
C7 complement component 7
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC85B coiled-coil domain containing 85B
CCNB2 cyclin B2
CCND2 cyclin D2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CECR1 cat eye syndrome chromosome region, candidate 1
CENPF centromere protein F, 350/400kDa
CIT citron rho-interacting serine/threonine kinase
CKB creatine kinase, brain
CPA3 carboxypeptidase A3 (mast cell)
DCN decorin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPAS1 endothelial PAS domain protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FOLR1 folate receptor 1 (adult)
FOXM1 forkhead box M1
GREB1 growth regulation by estrogen in breast cancer 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HLA-B major histocompatibility complex, class I, B
HMGN3 high mobility group nucleosomal binding domain 3
HOPX HOP homeobox
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LIMCH1 LIM and calponin homology domains 1
LTF lactotransferrin
LUM lumican
MPC2 mitochondrial pyruvate carrier 2
MSLN mesothelin
MSMB microseminoprotein, beta-
MUC16 mucin 16, cell surface associated
NEK2 NIMA-related kinase 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLSCR1 phospholipid scramblase 1
PLSCR4 phospholipid scramblase 4
PPOX protoporphyrinogen oxidase
PRDX2 peroxiredoxin 2
PSAT1 phosphoserine aminotransferase 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TACSTD2 tumor-associated calcium signal transducer 2
TIMELESS timeless circadian clock
TMEM47 transmembrane protein 47
TNS1 tensin 1
TNS3 tensin 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
WFDC2 WAP four-disulfide core domain 2