BRD-K86301799_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K86301799_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
ENO2 enolase 2 (gamma, neuronal)
FAM129A family with sequence similarity 129, member A
FCGBP Fc fragment of IgG binding protein
GCLC glutamate-cysteine ligase, catalytic subunit
GPNMB glycoprotein (transmembrane) nmb
GSDMB gasdermin B
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KRT13 keratin 13, type I
LPAR6 lysophosphatidic acid receptor 6
MB myoglobin
MPZL2 myelin protein zero-like 2
NEB nebulin
NELL2 NEL-like 2 (chicken)
NUSAP1 nucleolar and spindle associated protein 1
PDGFRL platelet-derived growth factor receptor-like
RGCC regulator of cell cycle
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SELENBP1 selenium binding protein 1
SOD2 superoxide dismutase 2, mitochondrial
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
CCND2 cyclin D2
CXCL12 chemokine (C-X-C motif) ligand 12
CYR61 cysteine-rich, angiogenic inducer, 61
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
HACD2 3-hydroxyacyl-CoA dehydratase 2
LDLR low density lipoprotein receptor
MGLL monoglyceride lipase
NFIB nuclear factor I/B
PLA1A phospholipase A1 member A
PLA2G16 phospholipase A2, group XVI
RBP4 retinol binding protein 4, plasma
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPS27L ribosomal protein S27-like
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
STK26 serine/threonine protein kinase 26
TAGLN transgelin
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TSPYL5 TSPY-like 5
VCAN versican
WASF3 WAS protein family, member 3