BRD-K86269644_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K86269644_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG2 arginase 2
BASP1 brain abundant, membrane attached signal protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COLEC12 collectin sub-family member 12
EDNRA endothelin receptor type A
FXYD5 FXYD domain containing ion transport regulator 5
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFITM1 interferon induced transmembrane protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA6 integrin, alpha 6
LTA4H leukotriene A4 hydrolase
NMU neuromedin U
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLS1 plastin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC44A4 solute carrier family 44, member 4
SYNGR3 synaptogyrin 3
TMSB15A thymosin beta 15a
TUBB2B tubulin, beta 2B class IIb
VIM vimentin

decreased expression

Symbol Name
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
PUF60 poly-U binding splicing factor 60KDa
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
ZDHHC6 zinc finger, DHHC-type containing 6