BRD-K86269644_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

96 genes differentially expressed following the BRD-K86269644_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACTG2 actin, gamma 2, smooth muscle, enteric
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AHR aryl hydrocarbon receptor
AIM1 absent in melanoma 1
AKR1C3 aldo-keto reductase family 1, member C3
ALDOB aldolase B, fructose-bisphosphate
AREG amphiregulin
ARG2 arginase 2
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BEX4 brain expressed, X-linked 4
CA2 carbonic anhydrase II
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CXCL14 chemokine (C-X-C motif) ligand 14
EGLN3 egl-9 family hypoxia-inducible factor 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EVI2A ecotropic viral integration site 2A
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GNLY granulysin
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
HOXB2 homeobox B2
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
KRT23 keratin 23, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LY6H lymphocyte antigen 6 complex, locus H
MAN1A1 mannosidase, alpha, class 1A, member 1
MMD monocyte to macrophage differentiation-associated
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPTX2 neuronal pentraxin II
NRCAM neuronal cell adhesion molecule
NT5E 5'-nucleotidase, ecto (CD73)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTN pleiotrophin
RGCC regulator of cell cycle
RHOB ras homolog family member B
RNF167 ring finger protein 167
SDC1 syndecan 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGPP1 sphingosine-1-phosphate phosphatase 1
SHB Src homology 2 domain containing adaptor protein B
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNAI2 snail family zinc finger 2
SNX10 sorting nexin 10
SOCS2 suppressor of cytokine signaling 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SST somatostatin
STX1A syntaxin 1A (brain)
TMEM35 transmembrane protein 35
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
TSPAN7 tetraspanin 7
TTYH1 tweety family member 1
VNN1 vanin 1

decreased expression

Symbol Name
BCL7B B-cell CLL/lymphoma 7B
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
ERBB2 erb-b2 receptor tyrosine kinase 2
FAM46A family with sequence similarity 46, member A
FPGS folylpolyglutamate synthase
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
KANK2 KN motif and ankyrin repeat domains 2
LTBP3 latent transforming growth factor beta binding protein 3
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MED1 mediator complex subunit 1
MOK MOK protein kinase
MSRB2 methionine sulfoxide reductase B2
NME4 NME/NM23 nucleoside diphosphate kinase 4
NUP98 nucleoporin 98kDa
PIP prolactin-induced protein
RAD51C RAD51 paralog C
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SORBS3 sorbin and SH3 domain containing 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin