BRD-K86269644_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K86269644_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
C14ORF132 chromosome 14 open reading frame 132
CD24 CD24 molecule
CFD complement factor D (adipsin)
CHIC2 cysteine-rich hydrophobic domain 2
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LAPTM5 lysosomal protein transmembrane 5
LGALS4 lectin, galactoside-binding, soluble, 4
MAOB monoamine oxidase B
MSX1 msh homeobox 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SOX4 SRY (sex determining region Y)-box 4
SRGN serglycin
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
AKAP8 A kinase (PRKA) anchor protein 8
ATF5 activating transcription factor 5
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
QKI QKI, KH domain containing, RNA binding