BRD-K86110682_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K86110682_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CBS cystathionine-beta-synthase
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FTH1 ferritin, heavy polypeptide 1
GADD45B growth arrest and DNA-damage-inducible, beta
GDF15 growth differentiation factor 15
KRT23 keratin 23, type I
LXN latexin
MCUR1 mitochondrial calcium uniporter regulator 1
MFAP5 microfibrillar associated protein 5
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OBSL1 obscurin-like 1
PHGDH phosphoglycerate dehydrogenase
PPAP2C phosphatidic acid phosphatase type 2C
QPRT quinolinate phosphoribosyltransferase
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SULF1 sulfatase 1
TRPS1 trichorhinophalangeal syndrome I
VAT1 vesicle amine transport 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK1 adenylate kinase 1
BIRC5 baculoviral IAP repeat containing 5
CCNF cyclin F
CDC25A cell division cycle 25A
CX3CR1 chemokine (C-X3-C motif) receptor 1
DES desmin
HN1 hematological and neurological expressed 1
HOPX HOP homeobox
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IL1RN interleukin 1 receptor antagonist
MAGEB2 melanoma antigen family B2
NAV3 neuron navigator 3
NUP85 nucleoporin 85kDa
PMP22 peripheral myelin protein 22
SRSF6 serine/arginine-rich splicing factor 6
SYNE1 spectrin repeat containing, nuclear envelope 1
ZCCHC24 zinc finger, CCHC domain containing 24