BRD-K85853281_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

120 genes differentially expressed following the BRD-K85853281_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
COL1A2 collagen, type I, alpha 2
CRELD2 cysteine-rich with EGF-like domains 2
CTSZ cathepsin Z
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EGFL6 EGF-like-domain, multiple 6
FBXO11 F-box protein 11
FST follistatin
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ISOC1 isochorismatase domain containing 1
MAOA monoamine oxidase A
MEF2C myocyte enhancer factor 2C
PEG3 paternally expressed 3
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROSC proline synthetase co-transcribed homolog (bacterial)
RGCC regulator of cell cycle
STS steroid sulfatase (microsomal), isozyme S
TCF4 transcription factor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADNP activity-dependent neuroprotector homeobox
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKAP12 A kinase (PRKA) anchor protein 12
ARID4B AT rich interactive domain 4B (RBP1-like)
BAG5 BCL2-associated athanogene 5
CBR3 carbonyl reductase 3
CCNF cyclin F
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
EED embryonic ectoderm development
ENO2 enolase 2 (gamma, neuronal)
FASTKD5 FAST kinase domains 5
FOSL1 FOS-like antigen 1
FOXD1 forkhead box D1
FOXJ3 forkhead box J3
FZD7 frizzled class receptor 7
GATA3 GATA binding protein 3
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRWD1 glutamate-rich WD repeat containing 1
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP6 insulin-like growth factor binding protein 6
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JMJD6 jumonji domain containing 6
KAT7 K(lysine) acetyltransferase 7
KDM5B lysine (K)-specific demethylase 5B
KIN Kin17 DNA and RNA binding protein
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LAMB3 laminin, beta 3
LSG1 large 60S subunit nuclear export GTPase 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MARCKSL1 MARCKS-like 1
MED1 mediator complex subunit 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTSS1 metastasis suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDZK1 PDZ domain containing 1
PFKP phosphofructokinase, platelet
PPIF peptidylprolyl isomerase F
PROM1 prominin 1
RANBP6 RAN binding protein 6
RBM15 RNA binding motif protein 15
RGS2 regulator of G-protein signaling 2
RPP38 ribonuclease P/MRP 38kDa subunit
SACS sacsin molecular chaperone
SAV1 salvador family WW domain containing protein 1
SCAF8 SR-related CTD-associated factor 8
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SETD5 SET domain containing 5
SFRP1 secreted frizzled-related protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SNX11 sorting nexin 11
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
TACSTD2 tumor-associated calcium signal transducer 2
TBP TATA box binding protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TGFBR3 transforming growth factor, beta receptor III
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TMEM243 transmembrane protein 243, mitochondrial
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRAF4 TNF receptor-associated factor 4
UGCG UDP-glucose ceramide glucosyltransferase
USP1 ubiquitin specific peptidase 1
VCAM1 vascular cell adhesion molecule 1
VGLL4 vestigial-like family member 4
WEE1 WEE1 G2 checkpoint kinase
WIPF2 WAS/WASL interacting protein family, member 2
XBP1 X-box binding protein 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1