BRD-K85606544_neratinib_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

85 genes differentially expressed following the BRD-K85606544_neratinib_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA1 annexin A1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BHLHE41 basic helix-loop-helix family, member e41
CCNG2 cyclin G2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK14 cyclin-dependent kinase 14
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CKB creatine kinase, brain
CLDN3 claudin 3
CLU clusterin
CRABP2 cellular retinoic acid binding protein 2
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
EGFR epidermal growth factor receptor
FGFR3 fibroblast growth factor receptor 3
FOLR1 folate receptor 1 (adult)
FOXG1 forkhead box G1
FXYD3 FXYD domain containing ion transport regulator 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPM6B glycoprotein M6B
GRAMD1C GRAM domain containing 1C
GRB10 growth factor receptor-bound protein 10
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IL1R1 interleukin 1 receptor, type I
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMO4 LIM domain only 4
MAMLD1 mastermind-like domain containing 1
MECOM MDS1 and EVI1 complex locus
MYBPC1 myosin binding protein C, slow type
NEBL nebulette
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PALLD palladin, cytoskeletal associated protein
PEG10 paternally expressed 10
PSAT1 phosphoserine aminotransferase 1
PTCH1 patched 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TJP2 tight junction protein 2
TMPRSS3 transmembrane protease, serine 3
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
CA2 carbonic anhydrase II
CCND1 cyclin D1
CCNE2 cyclin E2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CTSH cathepsin H
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DUSP4 dual specificity phosphatase 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCMR Fc fragment of IgM receptor
GNAS GNAS complex locus
HES1 hes family bHLH transcription factor 1
IL13RA2 interleukin 13 receptor, alpha 2
IL24 interleukin 24
JADE2 jade family PHD finger 2
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAT2A methionine adenosyltransferase II, alpha
MMP3 matrix metallopeptidase 3
NELL2 NEL-like 2 (chicken)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PFDN4 prefoldin subunit 4
PLAC8 placenta-specific 8
PMP22 peripheral myelin protein 22
PNP purine nucleoside phosphorylase
PRKCB protein kinase C, beta
RPS27L ribosomal protein S27-like
SELL selectin L
SPRR1A small proline-rich protein 1A
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8