BRD-K85606544_neratinib_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K85606544_neratinib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
CADM1 cell adhesion molecule 1
CAST calpastatin
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CSTA cystatin A (stefin A)
DUSP3 dual specificity phosphatase 3
HBB hemoglobin, beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGHM immunoglobulin heavy constant mu
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT6A keratin 6A, type II
LTF lactotransferrin
LYZ lysozyme
PLAGL1 pleiomorphic adenoma gene-like 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CAPN2 calpain 2, (m/II) large subunit
CLDN1 claudin 1
DUSP4 dual specificity phosphatase 4
FOSL1 FOS-like antigen 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDN necdin, melanoma antigen (MAGE) family member
PHLDA1 pleckstrin homology-like domain, family A, member 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
SCUBE2 signal peptide, CUB domain, EGF-like 2
TES testin LIM domain protein
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1