BRD-K85013741_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K85013741_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BST2 bone marrow stromal cell antigen 2
CAPN3 calpain 3, (p94)
CASP7 caspase 7, apoptosis-related cysteine peptidase
CLIC4 chloride intracellular channel 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP22 dual specificity phosphatase 22
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERGIC2 ERGIC and golgi 2
FOLR1 folate receptor 1 (adult)
GOLGA8A golgin A8 family, member A
GREB1 growth regulation by estrogen in breast cancer 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
IFITM1 interferon induced transmembrane protein 1
IL6ST interleukin 6 signal transducer
KANK2 KN motif and ankyrin repeat domains 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIAA0125 KIAA0125
KRT19 keratin 19, type I
MBOAT7 membrane bound O-acyltransferase domain containing 7
MSMO1 methylsterol monooxygenase 1
NPC2 Niemann-Pick disease, type C2
OXTR oxytocin receptor
PURA purine-rich element binding protein A
RAD51C RAD51 paralog C
SLC16A6 solute carrier family 16, member 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
TBC1D4 TBC1 domain family, member 4
TBL1X transducin (beta)-like 1X-linked
TESC tescalcin
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ARL4C ADP-ribosylation factor-like 4C
ASRGL1 asparaginase like 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BMP2 bone morphogenetic protein 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLC Charcot-Leyden crystal galectin
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CTBP2 C-terminal binding protein 2
CTGF connective tissue growth factor
CXCL9 chemokine (C-X-C motif) ligand 9
DUOX2 dual oxidase 2
DUSP6 dual specificity phosphatase 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPAS1 endothelial PAS domain protein 1
EPN2 epsin 2
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
GRIA2 glutamate receptor, ionotropic, AMPA 2
H1FX H1 histone family, member X
HBB hemoglobin, beta
HDAC9 histone deacetylase 9
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
INSM1 insulinoma-associated 1
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KRT81 keratin 81, type II
LEFTY1 left-right determination factor 1
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MMP2 matrix metallopeptidase 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPTX2 neuronal pentraxin II
OLFM4 olfactomedin 4
OPHN1 oligophrenin 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
RTN1 reticulon 1
SDC2 syndecan 2
SORBS2 sorbin and SH3 domain containing 2
SOX11 SRY (sex determining region Y)-box 11
STC1 stanniocalcin 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TWIST1 twist family bHLH transcription factor 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)
ZNF423 zinc finger protein 423