BRD-K84987553_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K84987553_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
AZU1 azurocidin 1
BASP1 brain abundant, membrane attached signal protein 1
BLVRB biliverdin reductase B
CLDN10 claudin 10
CPB1 carboxypeptidase B1 (tissue)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DPP4 dipeptidyl-peptidase 4
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS1 growth arrest-specific 1
GCLM glutamate-cysteine ligase, modifier subunit
GNLY granulysin
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
KYNU kynureninase
MCOLN1 mucolipin 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
PENK proenkephalin
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SQSTM1 sequestosome 1
TLR4 toll-like receptor 4
TNPO1 transportin 1
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
WFS1 Wolfram syndrome 1 (wolframin)
XYLT1 xylosyltransferase I

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CDC42 cell division cycle 42
CTGF connective tissue growth factor
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP6 dual specificity phosphatase 6
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP1 fatty acid binding protein 1, liver
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KLF6 Kruppel-like factor 6
LAMB1 laminin, beta 1
LYZ lysozyme
NAV2 neuron navigator 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP1 receptor accessory protein 1
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)