BRD-K84895041_BMY 45778_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K84895041_BMY 45778_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADIRF adipogenesis regulatory factor
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BHLHE41 basic helix-loop-helix family, member e41
BLVRB biliverdin reductase B
CA1 carbonic anhydrase I
CANX calnexin
CD163 CD163 molecule
CTSL cathepsin L
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DHDDS dehydrodolichyl diphosphate synthase
EMX2 empty spiracles homeobox 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
FCGBP Fc fragment of IgG binding protein
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GOLT1B golgi transport 1B
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
IL32 interleukin 32
JAG1 jagged 1
LBH limb bud and heart development
LCN2 lipocalin 2
LY96 lymphocyte antigen 96
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP3 matrix metallopeptidase 3
MT1X metallothionein 1X
NID2 nidogen 2 (osteonidogen)
NQO1 NAD(P)H dehydrogenase, quinone 1
NUCB2 nucleobindin 2
RAD23B RAD23 homolog B (S. cerevisiae)
S100A9 S100 calcium binding protein A9
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A6 solute carrier family 16, member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SQSTM1 sequestosome 1
STC1 stanniocalcin 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
TSPYL5 TSPY-like 5
TTC39A tetratricopeptide repeat domain 39A
TUBB2A tubulin, beta 2A class IIa
VAT1 vesicle amine transport 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSH cathepsin H
DEPTOR DEP domain containing MTOR-interacting protein
DLC1 DLC1 Rho GTPase activating protein
DPYD dihydropyrimidine dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F2R coagulation factor II (thrombin) receptor
GPRC5A G protein-coupled receptor, class C, group 5, member A
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
MBOAT7 membrane bound O-acyltransferase domain containing 7
MGP matrix Gla protein
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NRGN neurogranin (protein kinase C substrate, RC3)
PBX3 pre-B-cell leukemia homeobox 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPA1 pyrophosphatase (inorganic) 1
PTMA prothymosin, alpha
RRM2 ribonucleotide reductase M2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SORBS2 sorbin and SH3 domain containing 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIAM1 T-cell lymphoma invasion and metastasis 1
TPM1 tropomyosin 1 (alpha)
VCAN versican