BRD-K84762162_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

113 genes differentially expressed following the BRD-K84762162_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADGRL2 adhesion G protein-coupled receptor L2
AGR2 anterior gradient 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ANXA2 annexin A2
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BASP1 brain abundant, membrane attached signal protein 1
BAX BCL2-associated X protein
BTG2 BTG family, member 2
C8ORF4 chromosome 8 open reading frame 4
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLCA4 chloride channel accessory 4
COCH cochlin
COL4A5 collagen, type IV, alpha 5
CSNK2A2 casein kinase 2, alpha prime polypeptide
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DST dystonin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHA2 EPH receptor A2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
FBN2 fibrillin 2
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAL galanin/GMAP prepropeptide
GPX3 glutathione peroxidase 3
GSE1 Gse1 coiled-coil protein
HBEGF heparin-binding EGF-like growth factor
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTA1 metastasis associated 1
MYO6 myosin VI
NOTCH1 notch 1
PDGFA platelet-derived growth factor alpha polypeptide
PLAC8 placenta-specific 8
PLAUR plasminogen activator, urokinase receptor
PPL periplakin
PTX3 pentraxin 3, long
RIOK3 RIO kinase 3
RRAD Ras-related associated with diabetes
SESN1 sestrin 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLPI secretory leukocyte peptidase inhibitor
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM255A transmembrane protein 255A
TSPAN8 tetraspanin 8
TWIST1 twist family bHLH transcription factor 1
YBX3 Y box binding protein 3
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADIRF adipogenesis regulatory factor
ANPEP alanyl (membrane) aminopeptidase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AUTS2 autism susceptibility candidate 2
CA12 carbonic anhydrase XII
CD200 CD200 molecule
CTBP2 C-terminal binding protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
FAM57A family with sequence similarity 57, member A
FAR2 fatty acyl CoA reductase 2
FGFR2 fibroblast growth factor receptor 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPR137B G protein-coupled receptor 137B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2BG histone cluster 1, H2bg
HIST1H4C histone cluster 1, H4c
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
KANK1 KN motif and ankyrin repeat domains 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLHL9 kelch-like family member 9
LAGE3 L antigen family, member 3
LAMP5 lysosomal-associated membrane protein family, member 5
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
METRN meteorin, glial cell differentiation regulator
MFAP5 microfibrillar associated protein 5
MT1F metallothionein 1F
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAT ornithine aminotransferase
PLA2G16 phospholipase A2, group XVI
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS1 regulator of G-protein signaling 1
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
TPBG trophoblast glycoprotein
TRPS1 trichorhinophalangeal syndrome I
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VCAM1 vascular cell adhesion molecule 1
XYLT1 xylosyltransferase I