BRD-K84709232_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K84709232_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
DDIT3 DNA-damage-inducible transcript 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
MAST2 microtubule associated serine/threonine kinase 2
MYBPC1 myosin binding protein C, slow type
NQO1 NAD(P)H dehydrogenase, quinone 1
PTX3 pentraxin 3, long
SFN stratifin
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
STC2 stanniocalcin 2
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADA adenosine deaminase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
RHOBTB3 Rho-related BTB domain containing 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase