BRD-K84450674_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K84450674_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
AKR1C3 aldo-keto reductase family 1, member C3
BTG1 B-cell translocation gene 1, anti-proliferative
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
COL6A3 collagen, type VI, alpha 3
CPA3 carboxypeptidase A3 (mast cell)
CTSZ cathepsin Z
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
ENO1 enolase 1, (alpha)
GSE1 Gse1 coiled-coil protein
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
LGALS1 lectin, galactoside-binding, soluble, 1
MAP7 microtubule-associated protein 7
MMP12 matrix metallopeptidase 12
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PBX1 pre-B-cell leukemia homeobox 1
S100A10 S100 calcium binding protein A10
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
TSPYL5 TSPY-like 5
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
C8ORF4 chromosome 8 open reading frame 4
CCDC86 coiled-coil domain containing 86
CFH complement factor H
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
GAS6 growth arrest-specific 6
IL1R1 interleukin 1 receptor, type I
KIF14 kinesin family member 14
MAN1A1 mannosidase, alpha, class 1A, member 1
MECOM MDS1 and EVI1 complex locus
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SYT1 synaptotagmin I
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMSB15A thymosin beta 15a