BRD-K84421793_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K84421793_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
ASNS asparagine synthetase (glutamine-hydrolyzing)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTGF connective tissue growth factor
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DPYSL3 dihydropyrimidinase-like 3
F13A1 coagulation factor XIII, A1 polypeptide
HMOX1 heme oxygenase 1
KLF5 Kruppel-like factor 5 (intestinal)
MGP matrix Gla protein
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PHGDH phosphoglycerate dehydrogenase
PRUNE2 prune homolog 2 (Drosophila)
PSAT1 phosphoserine aminotransferase 1
PTX3 pentraxin 3, long
PXDN peroxidasin
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SH3YL1 SH3 and SYLF domain containing 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SULF1 sulfatase 1
TPSAB1 tryptase alpha/beta 1
TSC22D3 TSC22 domain family, member 3
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
CPE carboxypeptidase E
EIF5A eukaryotic translation initiation factor 5A
H2AFV H2A histone family, member V
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLF hepatic leukemia factor
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
KIF2C kinesin family member 2C