BRD-K84421793_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K84421793_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CD24 CD24 molecule
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
EPRS glutamyl-prolyl-tRNA synthetase
FN1 fibronectin 1
FXYD6 FXYD domain containing ion transport regulator 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PCP4 Purkinje cell protein 4
PPAP2B phosphatidic acid phosphatase type 2B
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
STC2 stanniocalcin 2
TFF3 trefoil factor 3 (intestinal)
TMEM2 transmembrane protein 2

decreased expression

Symbol Name
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CD59 CD59 molecule, complement regulatory protein
FABP7 fatty acid binding protein 7, brain
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
JADE2 jade family PHD finger 2
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4