BRD-K84106030_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K84106030_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP5 acid phosphatase 5, tartrate resistant
ACPP acid phosphatase, prostate
ALOX5 arachidonate 5-lipoxygenase
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
BID BH3 interacting domain death agonist
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP4A charged multivesicular body protein 4A
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL5 chemokine (C-X-C motif) ligand 5
DAXX death-domain associated protein
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
H1F0 H1 histone family, member 0
HBD hemoglobin, delta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HSPA1A heat shock 70kDa protein 1A
KRT81 keratin 81, type II
LXN latexin
LYZ lysozyme
MAP7 microtubule-associated protein 7
MARS methionyl-tRNA synthetase
MCOLN1 mucolipin 1
MMP12 matrix metallopeptidase 12
MSMB microseminoprotein, beta-
OLFM4 olfactomedin 4
OSBPL10 oxysterol binding protein-like 10
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PLIN2 perilipin 2
PSAT1 phosphoserine aminotransferase 1
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SST somatostatin
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STC2 stanniocalcin 2
TBX3 T-box 3
TESK1 testis-specific kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM176B transmembrane protein 176B
TMEM47 transmembrane protein 47
TRIB3 tribbles pseudokinase 3
TSC22D1 TSC22 domain family, member 1
TYROBP TYRO protein tyrosine kinase binding protein
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
COL4A5 collagen, type IV, alpha 5
COL5A1 collagen, type V, alpha 1
CPNE3 copine III
CRISP3 cysteine-rich secretory protein 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
EGR3 early growth response 3
FOLR1 folate receptor 1 (adult)
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
KIAA0101 KIAA0101
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
MEIS1 Meis homeobox 1
MUC1 mucin 1, cell surface associated
MYO6 myosin VI
NPIPB3 nuclear pore complex interacting protein family, member B3
NQO1 NAD(P)H dehydrogenase, quinone 1
NUSAP1 nucleolar and spindle associated protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PFN2 profilin 2
PIP prolactin-induced protein
PLAC8 placenta-specific 8
PLAGL1 pleiomorphic adenoma gene-like 1
PODXL podocalyxin-like
RDX radixin
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SATB1 SATB homeobox 1
SLPI secretory leukocyte peptidase inhibitor
SMC1A structural maintenance of chromosomes 1A
SNRPE small nuclear ribonucleoprotein polypeptide E
SPINK1 serine peptidase inhibitor, Kazal type 1
STK26 serine/threonine protein kinase 26
TKT transketolase
TSPAN3 tetraspanin 3
TXN thioredoxin
TYMS thymidylate synthetase