BRD-K84106030_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

79 genes differentially expressed following the BRD-K84106030_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ARMCX1 armadillo repeat containing, X-linked 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CA2 carbonic anhydrase II
CD200 CD200 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CREM cAMP responsive element modulator
CRYAB crystallin, alpha B
CXCL10 chemokine (C-X-C motif) ligand 10
CYTIP cytohesin 1 interacting protein
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ESR1 estrogen receptor 1
FTH1 ferritin, heavy polypeptide 1
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GREB1 growth regulation by estrogen in breast cancer 1
GSTA1 glutathione S-transferase alpha 1
HBB hemoglobin, beta
HBD hemoglobin, delta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HSPA1A heat shock 70kDa protein 1A
ICAM2 intercellular adhesion molecule 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
ISG20 interferon stimulated exonuclease gene 20kDa
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
MCAM melanoma cell adhesion molecule
MEF2C myocyte enhancer factor 2C
MEST mesoderm specific transcript
MMP12 matrix metallopeptidase 12
MPO myeloperoxidase
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NEB nebulin
NEU1 sialidase 1 (lysosomal sialidase)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4B phosphodiesterase 4B, cAMP-specific
PDZK1 PDZ domain containing 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLIN2 perilipin 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRC protein tyrosine phosphatase, receptor type, C
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SRGN serglycin
STC2 stanniocalcin 2
TFF1 trefoil factor 1
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BACE2 beta-site APP-cleaving enzyme 2
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
EGFR epidermal growth factor receptor
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FAP fibroblast activation protein, alpha
FAR2 fatty acyl CoA reductase 2
FOLR1 folate receptor 1 (adult)
ISLR immunoglobulin superfamily containing leucine-rich repeat
KCTD12 potassium channel tetramerization domain containing 12
PCOLCE procollagen C-endopeptidase enhancer
SEPP1 selenoprotein P, plasma, 1
SPRY2 sprouty homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21