BRD-K83972459_JWE-035_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K83972459_JWE-035_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANOS1 anosmin 1
ARG1 arginase 1
BMP7 bone morphogenetic protein 7
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK14 cyclin-dependent kinase 14
CHI3L2 chitinase 3-like 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLPTM1 cleft lip and palate associated transmembrane protein 1
COCH cochlin
CYBB cytochrome b-245, beta polypeptide
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EFNB2 ephrin-B2
KLF4 Kruppel-like factor 4 (gut)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NLRP2 NLR family, pyrin domain containing 2
PLEC plectin
PMP2 peripheral myelin protein 2
PRKCA protein kinase C, alpha
PTGES prostaglandin E synthase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TCF4 transcription factor 4
TMC5 transmembrane channel-like 5
TMEM100 transmembrane protein 100
TMSB15A thymosin beta 15a
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ALB albumin
APOD apolipoprotein D
BHLHE41 basic helix-loop-helix family, member e41
CADM1 cell adhesion molecule 1
CCND2 cyclin D2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CTSZ cathepsin Z
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT3 DNA-damage-inducible transcript 3
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
ECM1 extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
EPHA3 EPH receptor A3
FAM60A family with sequence similarity 60, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
FST follistatin
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
IL1A interleukin 1, alpha
IPO13 importin 13
JUP junction plakoglobin
KLK5 kallikrein-related peptidase 5
KRT19 keratin 19, type I
LCN2 lipocalin 2
LMO2 LIM domain only 2 (rhombotin-like 1)
MAN1A1 mannosidase, alpha, class 1A, member 1
MEIS2 Meis homeobox 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PROM1 prominin 1
PTHLH parathyroid hormone-like hormone
RCAN1 regulator of calcineurin 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SETBP1 SET binding protein 1
SKAP2 src kinase associated phosphoprotein 2
SPON1 spondin 1, extracellular matrix protein
SSPN sarcospan
SST somatostatin
TMEM47 transmembrane protein 47
TPM4 tropomyosin 4
TRIM2 tripartite motif containing 2
VGLL1 vestigial-like family member 1
VTCN1 V-set domain containing T cell activation inhibitor 1