BRD-K83972459_JWE-035_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K83972459_JWE-035_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ASPN asporin
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
C14ORF132 chromosome 14 open reading frame 132
C6ORF48 chromosome 6 open reading frame 48
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CLTB clathrin, light chain B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
GAA glucosidase, alpha; acid
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIST1H1C histone cluster 1, H1c
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NR2F2 nuclear receptor subfamily 2, group F, member 2
PNMA1 paraneoplastic Ma antigen 1
POSTN periostin, osteoblast specific factor
PRAME preferentially expressed antigen in melanoma
RASA4 RAS p21 protein activator 4
SNAP25 synaptosomal-associated protein, 25kDa
STXBP1 syntaxin binding protein 1
TMEM176B transmembrane protein 176B
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb

decreased expression

Symbol Name
AK4 adenylate kinase 4
ARMCX2 armadillo repeat containing, X-linked 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD58 CD58 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRABP2 cellular retinoic acid binding protein 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENG endoglin
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FST follistatin
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
H1F0 H1 histone family, member 0
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KLK11 kallikrein-related peptidase 11
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
KRT7 keratin 7, type II
LTF lactotransferrin
MYB v-myb avian myeloblastosis viral oncogene homolog
NR1H2 nuclear receptor subfamily 1, group H, member 2
PAPD7 PAP associated domain containing 7
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIP prolactin-induced protein
S100A8 S100 calcium binding protein A8
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNX7 sorting nexin 7
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPM4 tropomyosin 4
VTCN1 V-set domain containing T cell activation inhibitor 1