BRD-K83963101_MLN-8054_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K83963101_MLN-8054_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAT1 adenosine deaminase, tRNA-specific 1
AQP3 aquaporin 3 (Gill blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
EDNRB endothelin receptor type B
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GAGE3 G antigen 3
GLIPR1 GLI pathogenesis-related 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
IL7R interleukin 7 receptor
KIF20A kinesin family member 20A
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NCK2 NCK adaptor protein 2
NEFL neurofilament, light polypeptide
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKD3 protein kinase D3
RHOBTB3 Rho-related BTB domain containing 3
SFRP1 secreted frizzled-related protein 1
SPTBN1 spectrin, beta, non-erythrocytic 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNC tenascin C
TNPO1 transportin 1
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
C10ORF10 chromosome 10 open reading frame 10
CCDC92 coiled-coil domain containing 92
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CYB5A cytochrome b5 type A (microsomal)
FASN fatty acid synthase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL32 interleukin 32
MMP9 matrix metallopeptidase 9
NDRG1 N-myc downstream regulated 1
RAI14 retinoic acid induced 14
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP4 secreted frizzled-related protein 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10