BRD-K83963101_MLN-8054_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the BRD-K83963101_MLN-8054_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BAX BCL2-associated X protein
BTG2 BTG family, member 2
CD44 CD44 molecule (Indian blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDB2 damage-specific DNA binding protein 2, 48kDa
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
GADD45A growth arrest and DNA-damage-inducible, alpha
GLIPR1 GLI pathogenesis-related 1
LAMB1 laminin, beta 1
MIR22HG MIR22 host gene
MT1E metallothionein 1E
MT1X metallothionein 1X
MT2A metallothionein 2A
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPS27L ribosomal protein S27-like
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM22 tripartite motif containing 22
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
BGN biglycan
CD36 CD36 molecule (thrombospondin receptor)
CDC45 cell division cycle 45
SEH1L SEH1-like (S. cerevisiae)
TXNDC9 thioredoxin domain containing 9
WIF1 WNT inhibitory factor 1