BRD-K83963101_MLN-8054_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K83963101_MLN-8054_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AUTS2 autism susceptibility candidate 2
BAG1 BCL2-associated athanogene
BEX1 brain expressed, X-linked 1
CCND1 cyclin D1
CD200 CD200 molecule
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCT dopachrome tautomerase
DDB2 damage-specific DNA binding protein 2, 48kDa
FAM46A family with sequence similarity 46, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FN1 fibronectin 1
GPC3 glypican 3
HES1 hes family bHLH transcription factor 1
IGFBP5 insulin-like growth factor binding protein 5
LTA4H leukotriene A4 hydrolase
LTBP2 latent transforming growth factor beta binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MLANA melan-A
NEFL neurofilament, light polypeptide
NTS neurotensin
OLFM1 olfactomedin 1
PKM pyruvate kinase, muscle
POSTN periostin, osteoblast specific factor
PPOX protoporphyrinogen oxidase
PRODH proline dehydrogenase (oxidase) 1
PTCH1 patched 1
QPCT glutaminyl-peptide cyclotransferase
RPS27L ribosomal protein S27-like
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TFF1 trefoil factor 1
TMEM97 transmembrane protein 97
TPD52L1 tumor protein D52-like 1
TRIB2 tribbles pseudokinase 2
TRIM22 tripartite motif containing 22
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZMAT3 zinc finger, matrin-type 3
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
BAD BCL2-associated agonist of cell death
C1R complement component 1, r subcomponent
DCN decorin
DPP4 dipeptidyl-peptidase 4
DPT dermatopontin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FMO5 flavin containing monooxygenase 5
GAS1 growth arrest-specific 1
HAT1 histone acetyltransferase 1
IL13RA2 interleukin 13 receptor, alpha 2
IL6ST interleukin 6 signal transducer
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MT1E metallothionein 1E
MT1F metallothionein 1F
MYBPC1 myosin binding protein C, slow type
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NSDHL NAD(P) dependent steroid dehydrogenase-like
OSMR oncostatin M receptor
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
SYPL1 synaptophysin-like 1
TBX3 T-box 3
TF transferrin