BRD-K83816656_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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60 genes differentially expressed following the BRD-K83816656_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AKR1C3 aldo-keto reductase family 1, member C3
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
APOA2 apolipoprotein A-II
APOB apolipoprotein B
BATF3 basic leucine zipper transcription factor, ATF-like 3
BEX4 brain expressed, X-linked 4
C5ORF30 chromosome 5 open reading frame 30
CA12 carbonic anhydrase XII
COCH cochlin
DSP desmoplakin
ELOVL2 ELOVL fatty acid elongase 2
ENO2 enolase 2 (gamma, neuronal)
F12 coagulation factor XII (Hageman factor)
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FYB FYN binding protein
HACD2 3-hydroxyacyl-CoA dehydratase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IFRD1 interferon-related developmental regulator 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IQGAP2 IQ motif containing GTPase activating protein 2
ISG20 interferon stimulated exonuclease gene 20kDa
IVNS1ABP influenza virus NS1A binding protein
LEF1 lymphoid enhancer-binding factor 1
MDK midkine (neurite growth-promoting factor 2)
MFAP2 microfibrillar-associated protein 2
NGRN neugrin, neurite outgrowth associated
NRN1 neuritin 1
ODC1 ornithine decarboxylase 1
OPN3 opsin 3
PHACTR1 phosphatase and actin regulator 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
POSTN periostin, osteoblast specific factor
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RALB v-ral simian leukemia viral oncogene homolog B
S100A14 S100 calcium binding protein A14
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
STC2 stanniocalcin 2
SYBU syntabulin (syntaxin-interacting)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TPD52 tumor protein D52
TUBB2B tubulin, beta 2B class IIb
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
PDZK1IP1 PDZK1 interacting protein 1
PLAU plasminogen activator, urokinase
PTPRD protein tyrosine phosphatase, receptor type, D
RPL39L ribosomal protein L39-like
SDC4 syndecan 4
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
TARP TCR gamma alternate reading frame protein
TLR4 toll-like receptor 4
TXNDC9 thioredoxin domain containing 9