BRD-K83670234_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K83670234_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
AEBP1 AE binding protein 1
ANOS1 anosmin 1
ANXA4 annexin A4
ATF3 activating transcription factor 3
C3 complement component 3
CA2 carbonic anhydrase II
CCND2 cyclin D2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM171A1 family with sequence similarity 171, member A1
FAS Fas cell surface death receptor
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
IER3 immediate early response 3
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MGST3 microsomal glutathione S-transferase 3
MMP9 matrix metallopeptidase 9
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SGK1 serum/glucocorticoid regulated kinase 1
SOD2 superoxide dismutase 2, mitochondrial
SPARCL1 SPARC-like 1 (hevin)
TXNIP thioredoxin interacting protein
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BASP1 brain abundant, membrane attached signal protein 1
CBR3 carbonyl reductase 3
CCNF cyclin F
CDC25B cell division cycle 25B
CDC6 cell division cycle 6
CLTA clathrin, light chain A
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EMX2 empty spiracles homeobox 2
EXOSC4 exosome component 4
FAM57A family with sequence similarity 57, member A
GPRC5A G protein-coupled receptor, class C, group 5, member A
JMJD6 jumonji domain containing 6
KEAP1 kelch-like ECH-associated protein 1
MGLL monoglyceride lipase
NFIB nuclear factor I/B
NUP62 nucleoporin 62kDa
PFKP phosphofructokinase, platelet
RPS11 ribosomal protein S11
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
STX1A syntaxin 1A (brain)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCTA T-cell leukemia translocation altered
TGFBR3 transforming growth factor, beta receptor III
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRIM33 tripartite motif containing 33