BRD-K83509924_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K83509924_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACPP acid phosphatase, prostate
ARG2 arginase 2
BID BH3 interacting domain death agonist
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CEP57 centrosomal protein 57kDa
CHGB chromogranin B
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DES desmin
FGF13 fibroblast growth factor 13
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
H1F0 H1 histone family, member 0
HBB hemoglobin, beta
HIST1H2BG histone cluster 1, H2bg
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
LGALS1 lectin, galactoside-binding, soluble, 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MPO myeloperoxidase
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
NPY1R neuropeptide Y receptor Y1
OLFM4 olfactomedin 4
OSBPL10 oxysterol binding protein-like 10
PF4 platelet factor 4
PLIN2 perilipin 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTK2 protein tyrosine kinase 2
QPCT glutaminyl-peptide cyclotransferase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RPL39L ribosomal protein L39-like
RTN1 reticulon 1
S100P S100 calcium binding protein P
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SORBS2 sorbin and SH3 domain containing 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TSPYL5 TSPY-like 5
WNT4 wingless-type MMTV integration site family, member 4
XYLT1 xylosyltransferase I

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AHNAK2 AHNAK nucleoprotein 2
AK4 adenylate kinase 4
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
CFH complement factor H
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
CTSB cathepsin B
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EHBP1 EH domain binding protein 1
EIF5 eukaryotic translation initiation factor 5
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EREG epiregulin
FBN1 fibrillin 1
GBP1 guanylate binding protein 1, interferon-inducible
IVNS1ABP influenza virus NS1A binding protein
KCTD12 potassium channel tetramerization domain containing 12
LRRC15 leucine rich repeat containing 15
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP2 microfibrillar-associated protein 2
MXRA5 matrix-remodelling associated 5
NREP neuronal regeneration related protein
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDZD2 PDZ domain containing 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
PITX1 paired-like homeodomain 1
PLS3 plastin 3
POSTN periostin, osteoblast specific factor
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTN pleiotrophin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALGDS ral guanine nucleotide dissociation stimulator
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A2 S100 calcium binding protein A2
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
SYBU syntabulin (syntaxin-interacting)
TNS3 tensin 3
TSPAN3 tetraspanin 3
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)