BRD-K83336168_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K83336168_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BTG3 BTG family, member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CECR1 cat eye syndrome chromosome region, candidate 1
CKB creatine kinase, brain
CPA3 carboxypeptidase A3 (mast cell)
CSRP2 cysteine and glycine-rich protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
DPYSL3 dihydropyrimidinase-like 3
ECM1 extracellular matrix protein 1
EIF4A1 eukaryotic translation initiation factor 4A1
ELANE elastase, neutrophil expressed
FABP1 fatty acid binding protein 1, liver
FOS FBJ murine osteosarcoma viral oncogene homolog
GAS6 growth arrest-specific 6
GBP1 guanylate binding protein 1, interferon-inducible
H3F3B H3 histone, family 3B (H3.3B)
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IGFBP7 insulin-like growth factor binding protein 7
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LOC100505650 uncharacterized LOC100505650
MT1F metallothionein 1F
MT1X metallothionein 1X
PAWR PRKC, apoptosis, WT1, regulator
PRTN3 proteinase 3
RGCC regulator of cell cycle
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TCF4 transcription factor 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMCX6 armadillo repeat containing, X-linked 6
ARMT1 acidic residue methyltransferase 1
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF1 activating transcription factor 1
B3GNT1
BAMBI BMP and activin membrane-bound inhibitor
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CCNG2 cyclin G2
CD164 CD164 molecule, sialomucin
CD58 CD58 molecule
CDK19 cyclin-dependent kinase 19
CHSY1 chondroitin sulfate synthase 1
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COMMD8 COMM domain containing 8
CPNE3 copine III
CYB561 cytochrome b561
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCK deoxycytidine kinase
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM63A family with sequence similarity 63, member A
FOXA1 forkhead box A1
GATA3 GATA binding protein 3
GMFB glia maturation factor, beta
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLPH3L golgi phosphoprotein 3-like
HNMT histamine N-methyltransferase
HSPA13 heat shock protein 70kDa family, member 13
IER3 immediate early response 3
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK6 mitogen-activated protein kinase 6
MED28 mediator complex subunit 28
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGP matrix Gla protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NCOA3 nuclear receptor coactivator 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PCNA proliferating cell nuclear antigen
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PRSS23 protease, serine, 23
PTGES prostaglandin E synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RNASE4 ribonuclease, RNase A family, 4
RNF139 ring finger protein 139
RYBP RING1 and YY1 binding protein
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX4 SRY (sex determining region Y)-box 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM2D3 TM2 domain containing 3
TMEM168 transmembrane protein 168
TSPAN6 tetraspanin 6
TXNDC9 thioredoxin domain containing 9
UGCG UDP-glucose ceramide glucosyltransferase
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28