BRD-K83336168_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K83336168_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8 A kinase (PRKA) anchor protein 8
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAG3 BCL2-associated athanogene 3
CAPN2 calpain 2, (m/II) large subunit
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN10 claudin 10
CP ceruloplasmin (ferroxidase)
CSRP2 cysteine and glycine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLUD1 glutamate dehydrogenase 1
GOLM1 golgi membrane protein 1
H2BFS H2B histone family, member S (pseudogene)
H3F3B H3 histone, family 3B (H3.3B)
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IER5 immediate early response 5
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
KLF4 Kruppel-like factor 4 (gut)
MFAP5 microfibrillar associated protein 5
MSX1 msh homeobox 1
NT5E 5'-nucleotidase, ecto (CD73)
ODC1 ornithine decarboxylase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
S100A10 S100 calcium binding protein A10
SCPEP1 serine carboxypeptidase 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFN stratifin
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TARBP1 TAR (HIV-1) RNA binding protein 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)

decreased expression

Symbol Name
CALB1 calbindin 1, 28kDa
CANT1 calcium activated nucleotidase 1
CCR7 chemokine (C-C motif) receptor 7
CD164 CD164 molecule, sialomucin
CD59 CD59 molecule, complement regulatory protein
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCK deoxycytidine kinase
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUOX2 dual oxidase 2
FCGBP Fc fragment of IgG binding protein
GPX2 glutathione peroxidase 2
IER3 immediate early response 3
KANK1 KN motif and ankyrin repeat domains 1
KLHL9 kelch-like family member 9
KRT20 keratin 20, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIPG lipase, endothelial
LTBP1 latent transforming growth factor beta binding protein 1
MGP matrix Gla protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYRF myelin regulatory factor
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PBX1 pre-B-cell leukemia homeobox 1
PCP4 Purkinje cell protein 4
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QKI QKI, KH domain containing, RNA binding
REG1A regenerating islet-derived 1 alpha
RGS2 regulator of G-protein signaling 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SOX4 SRY (sex determining region Y)-box 4
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WFDC1 WAP four-disulfide core domain 1