BRD-K83213280_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K83213280_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CRIP2 cysteine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FBXO11 F-box protein 11
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
IFRD1 interferon-related developmental regulator 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
MPO myeloperoxidase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PHGDH phosphoglycerate dehydrogenase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PSAT1 phosphoserine aminotransferase 1
PTHLH parathyroid hormone-like hormone
PXDN peroxidasin
SERINC3 serine incorporator 3
SFRP4 secreted frizzled-related protein 4
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
STC2 stanniocalcin 2
TAGLN transgelin
THBS2 thrombospondin 2
TSC22D3 TSC22 domain family, member 3
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
ZHX2 zinc fingers and homeoboxes 2

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDK1 cyclin-dependent kinase 1
COCH cochlin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HOXB2 homeobox B2
KIF20A kinesin family member 20A
LMNB1 lamin B1
MELK maternal embryonic leucine zipper kinase
PLBD1 phospholipase B domain containing 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRC1 protein regulator of cytokinesis 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
SLIRP SRA stem-loop interacting RNA binding protein
SMAGP small cell adhesion glycoprotein
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCF4 transcription factor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UGCG UDP-glucose ceramide glucosyltransferase