BRD-K83048312_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K83048312_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CCL19 chemokine (C-C motif) ligand 19
CD36 CD36 molecule (thrombospondin receptor)
EIF4B eukaryotic translation initiation factor 4B
FASTKD5 FAST kinase domains 5
FBLN5 fibulin 5
GRN granulin
LAMP5 lysosomal-associated membrane protein family, member 5
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PDLIM5 PDZ and LIM domain 5
PNKP polynucleotide kinase 3'-phosphatase
SFRP1 secreted frizzled-related protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TBC1D4 TBC1 domain family, member 4
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
BLNK B-cell linker
CAV1 caveolin 1, caveolae protein, 22kDa
CD24 CD24 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CPA3 carboxypeptidase A3 (mast cell)
CYR61 cysteine-rich, angiogenic inducer, 61
GUSBP11 glucuronidase, beta pseudogene 11
IGL immunoglobulin lambda locus
KIAA0753 KIAA0753
LOXL2 lysyl oxidase-like 2
MMP2 matrix metallopeptidase 2
NPTX2 neuronal pentraxin II
PEG10 paternally expressed 10
PPOX protoporphyrinogen oxidase
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
SHB Src homology 2 domain containing adaptor protein B
SOX11 SRY (sex determining region Y)-box 11
SRGN serglycin
SULF1 sulfatase 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395