BRD-K82971429_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

16 genes differentially expressed following the BRD-K82971429_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CA12 carbonic anhydrase XII
DDIT4 DNA-damage-inducible transcript 4
FCGBP Fc fragment of IgG binding protein
HMOX1 heme oxygenase 1
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
MYLK myosin light chain kinase
PDGFA platelet-derived growth factor alpha polypeptide
TMEM45A transmembrane protein 45A
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
EPHA3 EPH receptor A3
HES1 hes family bHLH transcription factor 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)