BRD-K82928847_rocilinostat_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K82928847_rocilinostat_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ADGRG2 adhesion G protein-coupled receptor G2
AREG amphiregulin
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
C14ORF132 chromosome 14 open reading frame 132
CALR calreticulin
CAST calpastatin
CAV2 caveolin 2
CCNG2 cyclin G2
CD59 CD59 molecule, complement regulatory protein
CHL1 cell adhesion molecule L1-like
COCH cochlin
DHCR24 24-dehydrocholesterol reductase
EMP1 epithelial membrane protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EREG epiregulin
ETNK1 ethanolamine kinase 1
FGF13 fibroblast growth factor 13
FMO2 flavin containing monooxygenase 2 (non-functional)
GRN granulin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
KRT23 keratin 23, type I
LYPD1 LY6/PLAUR domain containing 1
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NEBL nebulette
NRN1 neuritin 1
SELENBP1 selenium binding protein 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TMSB15A thymosin beta 15a
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TOX3 TOX high mobility group box family member 3
TRIM2 tripartite motif containing 2
USP6NL USP6 N-terminal like
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
CD9 CD9 molecule
CX3CR1 chemokine (C-X3-C motif) receptor 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IRS2 insulin receptor substrate 2
LIMCH1 LIM and calponin homology domains 1
NPEPL1 aminopeptidase-like 1
PDLIM1 PDZ and LIM domain 1
PLAT plasminogen activator, tissue
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
SCUBE2 signal peptide, CUB domain, EGF-like 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TUSC3 tumor suppressor candidate 3
WDR7 WD repeat domain 7