BRD-K82928847_rocilinostat_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K82928847_rocilinostat_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AQP1 aquaporin 1 (Colton blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BASP1 brain abundant, membrane attached signal protein 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRYAB crystallin, alpha B
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
FABP7 fatty acid binding protein 7, brain
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
GLRX glutaredoxin (thioltransferase)
GNAS GNAS complex locus
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HNMT histamine N-methyltransferase
HOPX HOP homeobox
HSPB1 heat shock 27kDa protein 1
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
LTF lactotransferrin
MEGF9 multiple EGF-like-domains 9
MID1 midline 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MT1X metallothionein 1X
NCAM1 neural cell adhesion molecule 1
NRN1 neuritin 1
PIH1D1 PIH1 domain containing 1
PIP prolactin-induced protein
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDX2 peroxiredoxin 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN2 reticulon 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TCTA T-cell leukemia translocation altered
TFPI2 tissue factor pathway inhibitor 2
TRIL TLR4 interactor with leucine-rich repeats
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WDTC1 WD and tetratricopeptide repeats 1
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATF5 activating transcription factor 5
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
C6ORF62 chromosome 6 open reading frame 62
CD9 CD9 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COL5A2 collagen, type V, alpha 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
ENAH enabled homolog (Drosophila)
GDF15 growth differentiation factor 15
IFRD2 interferon-related developmental regulator 2
IL7R interleukin 7 receptor
IPO13 importin 13
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAWR PRKC, apoptosis, WT1, regulator
PDLIM5 PDZ and LIM domain 5
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOCS2 suppressor of cytokine signaling 2
SULF1 sulfatase 1
TARP TCR gamma alternate reading frame protein
TGFBI transforming growth factor, beta-induced, 68kDa
TIMELESS timeless circadian clock
TPR translocated promoter region, nuclear basket protein
XIST X inactive specific transcript (non-protein coding)