BRD-K82837433_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K82837433_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ATF3 activating transcription factor 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
CCND2 cyclin D2
CCNG1 cyclin G1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
ENO2 enolase 2 (gamma, neuronal)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXO3 forkhead box O3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF15 growth differentiation factor 15
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
GREM1 gremlin 1, DAN family BMP antagonist
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
ITM2C integral membrane protein 2C
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT20 keratin 20, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MFAP5 microfibrillar associated protein 5
MXI1 MAX interactor 1, dimerization protein
NCAM1 neural cell adhesion molecule 1
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM4 olfactomedin 4
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PCP4 Purkinje cell protein 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PERP PERP, TP53 apoptosis effector
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RAB21 RAB21, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPS27L ribosomal protein S27-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SESN1 sestrin 1
SIK1 salt-inducible kinase 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX4 SRY (sex determining region Y)-box 4
STC1 stanniocalcin 1
TF transferrin
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
VEGFA vascular endothelial growth factor A
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
AK1 adenylate kinase 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BIRC5 baculoviral IAP repeat containing 5
C6ORF62 chromosome 6 open reading frame 62
C7 complement component 7
CDCA3 cell division cycle associated 3
CDKN3 cyclin-dependent kinase inhibitor 3
CKS2 CDC28 protein kinase regulatory subunit 2
COL3A1 collagen, type III, alpha 1
DLC1 DLC1 Rho GTPase activating protein
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
GLIPR1 GLI pathogenesis-related 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HOXC6 homeobox C6
IRF8 interferon regulatory factor 8
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIF20A kinesin family member 20A
KRT15 keratin 15, type I
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
PRSS23 protease, serine, 23
S100A2 S100 calcium binding protein A2
SFTPB surfactant protein B
TM4SF1 transmembrane 4 L six family member 1