BRD-K82837433_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

114 genes differentially expressed following the BRD-K82837433_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AUTS2 autism susceptibility candidate 2
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA1 carbonic anhydrase I
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN3 claudin 3
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP6 dual specificity phosphatase 6
EFHD1 EF-hand domain family, member D1
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM13A family with sequence similarity 13, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FXYD3 FXYD domain containing ion transport regulator 3
GATA6 GATA binding protein 6
GLRX glutaredoxin (thioltransferase)
GSE1 Gse1 coiled-coil protein
HBEGF heparin-binding EGF-like growth factor
HEPH hephaestin
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
IL1A interleukin 1, alpha
INHBA inhibin, beta A
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
MEF2A myocyte enhancer factor 2A
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
MYC v-myc avian myelocytomatosis viral oncogene homolog
MZB1 marginal zone B and B1 cell-specific protein
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI2 peptidyl arginine deiminase, type II
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGK1 phosphoglycerate kinase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2B phosphatidic acid phosphatase type 2B
RNASE4 ribonuclease, RNase A family, 4
SATB2 SATB homeobox 2
SELENBP1 selenium binding protein 1
SERTAD2 SERTA domain containing 2
SIK1 salt-inducible kinase 1
SORBS2 sorbin and SH3 domain containing 2
STC1 stanniocalcin 1
STK38L serine/threonine kinase 38 like
TANK TRAF family member-associated NFKB activator
TFF3 trefoil factor 3 (intestinal)
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
CDC25B cell division cycle 25B
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
COX11 COX11 cytochrome c oxidase copper chaperone
DACH1 dachshund family transcription factor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EMP3 epithelial membrane protein 3
FBLN1 fibulin 1
GTSE1 G-2 and S-phase expressed 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LBR lamin B receptor
MARCKS myristoylated alanine-rich protein kinase C substrate
MLEC malectin
MPZL1 myelin protein zero-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NUP62 nucleoporin 62kDa
PLK1 polo-like kinase 1
PON2 paraoxonase 2
QPCT glutaminyl-peptide cyclotransferase
RAD9A RAD9 homolog A (S. pombe)
S100A10 S100 calcium binding protein A10
SCML1 sex comb on midleg-like 1 (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAM1 translocation associated membrane protein 1
UBE2S ubiquitin-conjugating enzyme E2S
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1