BRD-K82823804_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K82823804_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
BIRC3 baculoviral IAP repeat containing 3
BTG2 BTG family, member 2
CD9 CD9 molecule
CEP57 centrosomal protein 57kDa
CES1 carboxylesterase 1
CHRDL1 chordin-like 1
CRABP2 cellular retinoic acid binding protein 2
CTGF connective tissue growth factor
CUEDC1 CUE domain containing 1
CXCL10 chemokine (C-X-C motif) ligand 10
DCLK1 doublecortin-like kinase 1
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
EGFR epidermal growth factor receptor
FAM63A family with sequence similarity 63, member A
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FN1 fibronectin 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
IER3 immediate early response 3
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KLF6 Kruppel-like factor 6
LGALS8 lectin, galactoside-binding, soluble, 8
MEST mesoderm specific transcript
MTSS1 metastasis suppressor 1
MX1 MX dynamin-like GTPase 1
NEB nebulin
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORC1 origin recognition complex, subunit 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RGS2 regulator of G-protein signaling 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
STK26 serine/threonine protein kinase 26
THBS1 thrombospondin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
TRIM22 tripartite motif containing 22
TSPAN1 tetraspanin 1
TXNIP thioredoxin interacting protein
YBX3 Y box binding protein 3

decreased expression

Symbol Name
CDC42 cell division cycle 42
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
DIO2 deiodinase, iodothyronine, type II
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYNLL1 dynein, light chain, LC8-type 1
EXO1 exonuclease 1
FERMT2 fermitin family member 2
GCH1 GTP cyclohydrolase 1
GRWD1 glutamate-rich WD repeat containing 1
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
JMJD6 jumonji domain containing 6
KIAA1033 KIAA1033
LAMB1 laminin, beta 1
LAPTM4B lysosomal protein transmembrane 4 beta
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTBP1 latent transforming growth factor beta binding protein 1
MAGEA3 melanoma antigen family A3
MBD2 methyl-CpG binding domain protein 2
MFSD10 major facilitator superfamily domain containing 10
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MXRA7 matrix-remodelling associated 7
MYH10 myosin, heavy chain 10, non-muscle
NR2F1 nuclear receptor subfamily 2, group F, member 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
RAB15 RAB15, member RAS oncogene family
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF167 ring finger protein 167
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SET SET nuclear proto-oncogene
SFPQ splicing factor proline/glutamine-rich
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRSF2 serine/arginine-rich splicing factor 2
STX1A syntaxin 1A (brain)
UGDH UDP-glucose 6-dehydrogenase
ZMIZ1 zinc finger, MIZ-type containing 1