BRD-K82823804_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K82823804_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ASNS asparagine synthetase (glutamine-hydrolyzing)
CDK7 cyclin-dependent kinase 7
CLIC4 chloride intracellular channel 4
CRIP1 cysteine-rich protein 1 (intestinal)
DDIT4 DNA-damage-inducible transcript 4
GAGE3 G antigen 3
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIST1H2AC histone cluster 1, H2ac
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LGALS1 lectin, galactoside-binding, soluble, 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PSAT1 phosphoserine aminotransferase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AUTS2 autism susceptibility candidate 2
C1R complement component 1, r subcomponent
C6ORF62 chromosome 6 open reading frame 62
CDC25A cell division cycle 25A
CFI complement factor I
CTPS1 CTP synthase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DUSP6 dual specificity phosphatase 6
FBLN1 fibulin 1
FOSL1 FOS-like antigen 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
HES1 hes family bHLH transcription factor 1
HSPA1A heat shock 70kDa protein 1A
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MMP7 matrix metallopeptidase 7
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NKX3-1 NK3 homeobox 1
NUP62 nucleoporin 62kDa
PPIF peptidylprolyl isomerase F
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SET SET nuclear proto-oncogene
SFN stratifin
SOX4 SRY (sex determining region Y)-box 4
SPRY2 sprouty homolog 2 (Drosophila)
SRM spermidine synthase
SRPRB signal recognition particle receptor, B subunit
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TMEM109 transmembrane protein 109
WWTR1 WW domain containing transcription regulator 1
ZFP36L1 ZFP36 ring finger protein-like 1