BRD-K82746043_ABT-263_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K82746043_ABT-263_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADGRF5 adhesion G protein-coupled receptor F5
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD200 CD200 molecule
CD24 CD24 molecule
CKB creatine kinase, brain
CLIC5 chloride intracellular channel 5
CXCL9 chemokine (C-X-C motif) ligand 9
DUSP4 dual specificity phosphatase 4
FCGBP Fc fragment of IgG binding protein
FOXO1 forkhead box O1
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H2BD histone cluster 1, H2bd
HLA-DMB major histocompatibility complex, class II, DM beta
INHBB inhibin, beta B
IPO13 importin 13
KRT81 keratin 81, type II
LPAR6 lysophosphatidic acid receptor 6
MMP7 matrix metallopeptidase 7
MT1F metallothionein 1F
NEBL nebulette
NELL2 NEL-like 2 (chicken)
NT5E 5'-nucleotidase, ecto (CD73)
PARM1 prostate androgen-regulated mucin-like protein 1
PLN phospholamban
PON2 paraoxonase 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRUNE2 prune homolog 2 (Drosophila)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAP1GAP RAP1 GTPase activating protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE6 ribonuclease, RNase A family, k6
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RTN1 reticulon 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TACC2 transforming, acidic coiled-coil containing protein 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
BST2 bone marrow stromal cell antigen 2
C6ORF48 chromosome 6 open reading frame 48
COL4A5 collagen, type IV, alpha 5
CRIP1 cysteine-rich protein 1 (intestinal)
DMD dystrophin
ECI2 enoyl-CoA delta isomerase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
ERAP2 endoplasmic reticulum aminopeptidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
HLTF helicase-like transcription factor
LAGE3 L antigen family, member 3
NAV3 neuron navigator 3
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NREP neuronal regeneration related protein
PDZK1 PDZ domain containing 1
PLAC8 placenta-specific 8
WNT5A wingless-type MMTV integration site family, member 5A