BRD-K82580504_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K82580504_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
BHLHE41 basic helix-loop-helix family, member e41
BTBD3 BTB (POZ) domain containing 3
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
EFNB2 ephrin-B2
FAM134B family with sequence similarity 134, member B
FCGBP Fc fragment of IgG binding protein
GAS6 growth arrest-specific 6
GJA1 gap junction protein, alpha 1, 43kDa
ITM2C integral membrane protein 2C
KRT14 keratin 14, type I
NELL2 NEL-like 2 (chicken)
PTX3 pentraxin 3, long
RGS1 regulator of G-protein signaling 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC38A1 solute carrier family 38, member 1
STMN2 stathmin 2
TSC22D1 TSC22 domain family, member 1
TXNIP thioredoxin interacting protein
VIM vimentin

decreased expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AKAP8 A kinase (PRKA) anchor protein 8
ARID4B AT rich interactive domain 4B (RBP1-like)
BPHL biphenyl hydrolase-like (serine hydrolase)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK1 checkpoint kinase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DES desmin
DST dystonin
EFHD1 EF-hand domain family, member D1
ERBB4 erb-b2 receptor tyrosine kinase 4
EXOSC4 exosome component 4
FABP4 fatty acid binding protein 4, adipocyte
FOS FBJ murine osteosarcoma viral oncogene homolog
GSN gelsolin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KIAA0101 KIAA0101
KIAA0922 KIAA0922
MEIS2 Meis homeobox 2
MMP7 matrix metallopeptidase 7
MTF2 metal response element binding transcription factor 2
MYH11 myosin, heavy chain 11, smooth muscle
NEB nebulin
NSDHL NAD(P) dependent steroid dehydrogenase-like
PDLIM3 PDZ and LIM domain 3
PHYH phytanoyl-CoA 2-hydroxylase
PLN phospholamban
POSTN periostin, osteoblast specific factor
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRR15L proline rich 15-like
RPP38 ribonuclease P/MRP 38kDa subunit
RRM2 ribonucleotide reductase M2
RTN2 reticulon 2
TMEM5 transmembrane protein 5
VTCN1 V-set domain containing T cell activation inhibitor 1
ZMIZ1 zinc finger, MIZ-type containing 1