BRD-K82562631_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K82562631_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ANXA4 annexin A4
CD52 CD52 molecule
CRYAB crystallin, alpha B
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK3 dickkopf WNT signaling pathway inhibitor 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GMPR guanosine monophosphate reductase
GULP1 GULP, engulfment adaptor PTB domain containing 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTGDS prostaglandin D2 synthase 21kDa (brain)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC26A3 solute carrier family 26 (anion exchanger), member 3
VIM vimentin

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CEMIP cell migration inducing protein, hyaluronan binding
IGFBP4 insulin-like growth factor binding protein 4
INSR insulin receptor
KRT17 keratin 17, type I
KRT23 keratin 23, type I
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)