BRD-K82036761_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K82036761_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM9 ADAM metallopeptidase domain 9
ADM adrenomedullin
AREG amphiregulin
ATF3 activating transcription factor 3
C1QB complement component 1, q subcomponent, B chain
C5AR1 complement component 5a receptor 1
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRABP2 cellular retinoic acid binding protein 2
FAM69A family with sequence similarity 69, member A
FBN2 fibrillin 2
FBXO11 F-box protein 11
FOLR1 folate receptor 1 (adult)
GUSBP11 glucuronidase, beta pseudogene 11
GYPC glycophorin C (Gerbich blood group)
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INSIG1 insulin induced gene 1
LPL lipoprotein lipase
MAP2K5 mitogen-activated protein kinase kinase 5
NES nestin
NMU neuromedin U
NPR3 natriuretic peptide receptor 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX1 pre-B-cell leukemia homeobox 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEG10 paternally expressed 10
PGK1 phosphoglycerate kinase 1
RBPMS RNA binding protein with multiple splicing
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
STAB1 stabilin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB15A thymosin beta 15a
UGDH UDP-glucose 6-dehydrogenase
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
WT1 Wilms tumor 1

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
BEX1 brain expressed, X-linked 1
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
GPX2 glutathione peroxidase 2
HIST1H4C histone cluster 1, H4c
HLA-DMB major histocompatibility complex, class II, DM beta
LTF lactotransferrin
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPY1R neuropeptide Y receptor Y1
PCDH9 protocadherin 9
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RCAN1 regulator of calcineurin 1
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SF1 splicing factor 1
SPRY2 sprouty homolog 2 (Drosophila)
SRRM2 serine/arginine repetitive matrix 2
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX10 testis expressed 10
TFF1 trefoil factor 1
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
UGCG UDP-glucose ceramide glucosyltransferase