BRD-K81592585_DM-55-3 BRD-K81592585_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K81592585_DM-55-3 BRD-K81592585_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AHNAK AHNAK nucleoprotein
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD24 CD24 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PHGDH phosphoglycerate dehydrogenase
PTX3 pentraxin 3, long
S100A2 S100 calcium binding protein A2
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQLE squalene epoxidase
TRIB3 tribbles pseudokinase 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C8ORF4 chromosome 8 open reading frame 4
CFH complement factor H
FOLR1 folate receptor 1 (adult)
MTUS1 microtubule associated tumor suppressor 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PLCB4 phospholipase C, beta 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)