BRD-K81592585_DM-55-3 BRD-K81592585_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

42 genes differentially expressed following the BRD-K81592585_DM-55-3 BRD-K81592585_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CD14 CD14 molecule
CRYAB crystallin, alpha B
EIF4B eukaryotic translation initiation factor 4B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GRIA2 glutamate receptor, ionotropic, AMPA 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
MBP myelin basic protein
MEOX2 mesenchyme homeobox 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
NAMPT nicotinamide phosphoribosyltransferase
NDRG2 NDRG family member 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRF1 perforin 1 (pore forming protein)
RAD51C RAD51 paralog C
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ALB albumin
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
CADM1 cell adhesion molecule 1
CCNE2 cyclin E2
DKK3 dickkopf WNT signaling pathway inhibitor 3
FZD6 frizzled class receptor 6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGF1R insulin-like growth factor 1 receptor
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MPZL2 myelin protein zero-like 2
SDC1 syndecan 1
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TUSC3 tumor suppressor candidate 3