BRD-K81514393_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K81514393_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASPN asporin
ASS1 argininosuccinate synthase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CCND2 cyclin D2
FADS3 fatty acid desaturase 3
FGFR2 fibroblast growth factor receptor 2
GAGE3 G antigen 3
GPRC5B G protein-coupled receptor, class C, group 5, member B
H1F0 H1 histone family, member 0
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEF2C myocyte enhancer factor 2C
MKNK1 MAP kinase interacting serine/threonine kinase 1
MT1E metallothionein 1E
MT1G metallothionein 1G
NARFL nuclear prelamin A recognition factor-like
NIT1 nitrilase 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP prolactin-induced protein
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHB Src homology 2 domain containing adaptor protein B
SPRED2 sprouty-related, EVH1 domain containing 2
SULF1 sulfatase 1
THBS2 thrombospondin 2
TRIM13 tripartite motif containing 13
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
CA12 carbonic anhydrase XII
COCH cochlin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
MAP1B microtubule-associated protein 1B
MSX1 msh homeobox 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLK2 polo-like kinase 2
PNMA2 paraneoplastic Ma antigen 2
PSPH phosphoserine phosphatase
SLPI secretory leukocyte peptidase inhibitor