BRD-K81365078_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

54 genes differentially expressed following the BRD-K81365078_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CERK ceramide kinase
CKB creatine kinase, brain
COL11A1 collagen, type XI, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
KRT17 keratin 17, type I
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MTSS1 metastasis suppressor 1
NPR3 natriuretic peptide receptor 3
PIR pirin (iron-binding nuclear protein)
PROM1 prominin 1
RAD23B RAD23 homolog B (S. cerevisiae)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSKU tsukushi, small leucine rich proteoglycan
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
APOD apolipoprotein D
ATG3 autophagy related 3
CDH3 cadherin 3, type 1, P-cadherin (placental)
DCN decorin
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ETV5 ets variant 5
FBP1 fructose-1,6-bisphosphatase 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI27 interferon, alpha-inducible protein 27
KRT7 keratin 7, type II
MEIS1 Meis homeobox 1
NFIB nuclear factor I/B
NT5E 5'-nucleotidase, ecto (CD73)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTGDS prostaglandin D2 synthase 21kDa (brain)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SESN1 sestrin 1
SFRP1 secreted frizzled-related protein 1
SPRED2 sprouty-related, EVH1 domain containing 2
TNS3 tensin 3
VCAN versican
WIF1 WNT inhibitory factor 1