BRD-K81209159_HERNIARIN_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K81209159_HERNIARIN_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY1 adenylate cyclase 1 (brain)
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CA2 carbonic anhydrase II
CD200 CD200 molecule
CD24 CD24 molecule
CLDN8 claudin 8
FABP6 fatty acid binding protein 6, ileal
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IPO13 importin 13
JAG1 jagged 1
LOC100505650 uncharacterized LOC100505650
MAOA monoamine oxidase A
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
PEG3 paternally expressed 3
PELI1 pellino E3 ubiquitin protein ligase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PMM2 phosphomannomutase 2
PON3 paraoxonase 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
RGCC regulator of cell cycle
RTN1 reticulon 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
STEAP3 STEAP family member 3, metalloreductase
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AK4 adenylate kinase 4
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAG2 BCL2-associated athanogene 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLU clusterin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
EDNRB endothelin receptor type B
FAM46A family with sequence similarity 46, member A
FHL1 four and a half LIM domains 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPM6B glycoprotein M6B
HSPB8 heat shock 22kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IGHMBP2 immunoglobulin mu binding protein 2
IL6ST interleukin 6 signal transducer
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
MCUR1 mitochondrial calcium uniporter regulator 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRPS30 mitochondrial ribosomal protein S30
MSRB2 methionine sulfoxide reductase B2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NFIB nuclear factor I/B
NREP neuronal regeneration related protein
PLAC8 placenta-specific 8
QDPR quinoid dihydropteridine reductase
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SFN stratifin
SORD sorbitol dehydrogenase
SUB1 SUB1 homolog (S. cerevisiae)
TFF3 trefoil factor 3 (intestinal)
TYRP1 tyrosinase-related protein 1