BRD-K80981391_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K80981391_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBS cystathionine-beta-synthase
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUOX2 dual oxidase 2
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LY6D lymphocyte antigen 6 complex, locus D
MICALL1 MICAL-like 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PSAT1 phosphoserine aminotransferase 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SELL selectin L
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD6 SMAD family member 6
SNX11 sorting nexin 11
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THBD thrombomodulin
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ARG2 arginase 2
ARL4C ADP-ribosylation factor-like 4C
CD44 CD44 molecule (Indian blood group)
CP ceruloplasmin (ferroxidase)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
EGFL6 EGF-like-domain, multiple 6
FAP fibroblast activation protein, alpha
GNAS GNAS complex locus
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
PEG10 paternally expressed 10
PMM2 phosphomannomutase 2
POSTN periostin, osteoblast specific factor
RTN1 reticulon 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XIST X inactive specific transcript (non-protein coding)